***Sponsored by LFG Equities Corp
SER founders developed the first-generation of “PEGylated” drugs, which became the standard for delivery of protein drugs and has enabled 30 FDA approved products that have since generated over $140B in cumulative sales
Their lead product candidate, SER-252 for advanced Parkinsons Disease, is anticipated to enter clinical trials in 2025
SER has a Float of Just Over 3 Million According to the Leading Charting Site Finviz
Check Out the Investor Presentation Here
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Hello Everyone,
July has been an incredible month so far as we look to close it out this week with some names that you are going to want on your radar heading into August.
For tomorrow we have something brand new that I have never seen anyone feature before. This one is virtually undiscovered, which is a GREAT catalyst because of the size of the float, which is just over 3 million according to Finviz.
Pull up SER right away.
This NYSE AMEX company is sitting in it’s newly established trading zone and has held onto a big portion of some of it’s recent move.
This one has an interesting story behind it. The founders already did it once. This company was founded in 2007 and was largely funded by the founders and certain investors who followed the team to Serina after the successful exit (via acquisition by Nektar Therapeutics) of the founding team’s prior company, Shearwater Polymers.
At Shearwater, Serina co-founders Dr. Milton Harris and Dr. Michael Bentley developed the first-generation of “PEGylated” drugs. PEG (polyethylene glycol) technology became the standard for delivery of protein drugs and has enabled 30 FDA approved products that have since generated over $140B in cumulative sales. Serina was founded to engineer a next generation polymer therapeutic (our POZ PlatformTM) to address the limitations of PEG and other biocompatible polymer technologies — enabling new treatment paradigms for patients suffering from some of the world’s most challenging diseases.
You can see that this one made a significant move to the upside on underwhelming interest. Based on what we have seen we think that SER has the capability to move under the right circumstances. You really want to take a good look at this one. They have been releasing a ton of news this year and the company looks to be heading in the right direction.
Serina is in the process of developing proprietary drugs to treat neurological diseases. Their lead product candidate, SER-252 for advanced Parkinsons Disease, is anticipated to enter clinical trials in 2025. Their current discovery and development work includes a focus on unlocking the potential of cannabinoids and other molecules across a range of CNS indications and beyond. Their POZ platform partners are at the forefront in advancing novel RNA medicines in vaccine immunology, cancer immunoRX, and gene therapy.
Their proprietary POZ platform technology has been designed for programmable, targeted delivery of a broad range of small molecules. The technology has been clinically demonstrated to safely enable continuous drug delivery via a once weekly subcutaneous injection. The POZ platform is customizable, versatile and can be Serina is a clinical-stage biotechnology company developing a pipeline of wholly owned drug product candidates to treat neurological diseases and other indications. Serina’s POZ PlatformTM provides the potential to improve the integrated efficacy and safety profile of multiple modalities including small molecules, RNA-based therapeutics and antibody-based drug conjugates (ADCs).
The technology is based on a synthetic, water soluble, low viscosity polymer called poly(2-oxazoline). Serina’s POZ technology is engineered to provide greater control in drug loading and more precision in the rate of release of attached drugs delivered via subcutaneous injection. The therapeutic agents in Serina’s product candidates are typically well-understood and marketed drugs that are effective but are limited by pharmacokinetic profiles that can include toxicity, side effects and short half-life. Serina believes that by using POZ technology, drugs with narrow therapeutic windows can be designed to maintain more desirable and stable levels in the blood.
Serina’s POZ platform delivery technology has potential for use across a broad range of payloads and indications. Serina intends to advance additional applications of the POZ platform via out-licensing, co-development, or other partnership arrangements, including the non-exclusive license agreement with Pfizer, Inc. to use Serina’s POZ polymer technology for use in lipid nanoparticle drug (LNP) delivery formulations.
About SER-252 (POZ-apomorphine)
SER 252 is an investigational apomorphine therapy developed with Serina’s POZ platform and designed to provide continuous dopaminergic stimulation (CDS). CDS has been shown to reduce the severity of levodopa-related motor complications (dyskinesia) in Parkinson’s disease. Preclinical studies support the potential of SER 252 to provide CDS without skin reactions. Serina plans to advance SER 252 to clinical testing in 2025.
dosed via IV, SC or IM routes to address a broad range of clinical indications.
Our proprietary POZ platform is based on a synthetic, water soluble, low viscosity polymer called poly (2-oxazoline). During the synthesis steps, a predictable amount of drug is incorporated on the backbone of the polymer using pendant alkyne groups and metal catalyzed “click chemistry”.
POZ technology provides greater control in drug loading, and the rate of release of attached drugs can often be more precisely controlled. Drugs with narrow therapeutic windows can be designed to maintain more desirable and stable levels in the blood. The technology is optimized for small molecules and can also be applied to proteins, aptamers and other classes of molecules.
Their largest shareholder, Juvenescence Ltd., just secured $150 million in Series B financing led by M42, a global tech-enables health company headquartered in Abu Dhabi.
This significant investment and accompanying strategic alliance will accelerate Juvenescence’s mission to develop innovative therapies targeting age-related diseases and extending healthspan. As part of this partnership, Juvenescence and M42 will launch a drug development hub in Abu Dhabi, combining AI-enabled drug discovery with cutting-edge data and clinical infrastructure to speed the development of novel therapeutics.
Juvenescence has been a critical partner to Serina, providing strategic guidance and capital that has helped them advance their POZ Platform™ into the clinic.
NEWS
Serina Therapeutics Makes Grant to New Employee Under Inducement Plan
Jul 10, 2025
Serina Therapeutics Announces Date for 2025 Annual Stockholders Meeting
Jul 1, 2025
Serina Therapeutics to Present at FORCE Family Office Investor Webinar on June 26, 2025
Jun 23, 2025
Jun 17, 2025
Jun 17, 2025
Jun 9, 2025
Serina Therapeutics Appoints Stephen Brannan, M.D. to Board of Directors
May 22, 2025
Serina Therapeutics Makes Grants to New Employees Under Inducement Plan
May 14, 2025
Serina Therapeutics Reports First Quarter 2025 Financial Results and Provides Business Highlights
May 8, 2025
Serina Therapeutics to Present at JonesResearch Virtual CNS Day
Apr 29, 2025
Serina Therapeutics to Present at the 4th LNP Formulation & Process Development Summit
Apr 15, 2025
Apr 8, 2025
Serina Therapeutics to Present at the Jones Healthcare and Technology Innovation Conference
Apr 7, 2025
Serina Therapeutics Reports Full Year 2024 Financial Results and Recent Business Highlights
Mar 24, 2025
Serina Therapeutics to Present at the American Chemistry Society (ACS) Spring 2025 Meeting
Mar 24, 2025
Serina Therapeutics Appoints Dr. Jay Venkatesan to its Board of Directors
Feb 12, 2025
Feb 3, 2025
Serina Therapeutics Announces Sale of UniverXome Subsidiary
Jan 15, 2025
Serina Therapeutics Welcomes Karen J. Wilson to its Board of Directors
Jan 14, 2025
Dec 16, 2024
MANAGEMENT
Simba Gill, Ph.D.
Executive Chairman
Simba has a wealth of biotech and pharma experience in building companies and transformative platforms as well as developing products, having served in key executive roles at Maxygen, Systemix, Boehringer Mannheim and Celltech over his thirty-year career. He has served as a partner and advisor at Flagship Pioneering where he was the founding CEO of Evelo Biosciences and as a Venture Partner at TPG where he was Founder CEO of Moksh8 Pharmaceuticals. Simba is currently a board member at Foghorn Therapeutics (NASDAQ – FHTX) and Sensorium Therapeutics. He earned his MBA at INSEAD and received his Ph.D. from King’s College, London.
Steve Ledger
CEO and Director
Steve has served as CEO since March 2024 and CFO from March 2022 to March 2024. He has more than 35 years of experience as an investor, board member, advisor, and in operational roles with early-stage companies. He is a General Partner of Form & Fiction Ventures (FFV), a venture studio that launches and invests in startup and seed stage companies focused on socially responsible initiatives. He has served in investment management roles at Caldwell Sutter Capital, Tamalpais Partners, SF Sentry Securities, Kayne Anderson, and Fidelity Investments. Mr. Ledger received a B.A. in Economics from the University of Connecticut.
Randall
Randall Moreadith, M.D., Ph.D.
Chief Development Officer
Randall has served as Serina’s CDO since March 2024. He served as Serina’s President, CEO, and member of Serina’s board of directors from September 2010 to March 2024. Prior to Serina, Randall served in executive leadership roles including CDO at Nektar Therapeutics, CMO of Cardium Therapeutics, CMO at Renovis, and President / co-Founder of ThromboGenics (now Oxurion). Dr. Moreadith received his M.D. from Duke University and is trained clinically in Internal Medicine and Cardiovascular Diseases. Following his Fellowship in Cardiology at Duke University, he joined the laboratory of Professor Philip Leder where he was a Howard Hughes Medical Institute Fellow in Genetics at Harvard Medical School. Dr. Moreadith received his Ph.D. from Johns Hopkins University.
Greg Curhan
CFO
Greg joined Serina as CFO in August 2024. He has over 35 years of operational, financial, capital markets and strategic advisory experience in various sectors including Investment Banking and Medical Device/Life Sciences. Greg has been a Partner at FLG Partners since 2020. Also since 2020, Greg has served as the CFO for Curevo Vaccines, a private biotech company focused on infectious disease immunology. As CFO, Greg has managed Finance, Legal, HR, and Investor Relations functions for Public and Private companies. He has raised equity and debt capital for both private and public companies, completed numerous successful IPOs, and executed M&A transactions, both acquiring and divesting companies. He has also served in CEO, President and Board of Director capacities. Greg earned a BA degree in Economics from Dartmouth College.
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