xxii

***Sponsored by Shore Thing Media, LLC

Read the Investor Presentation HERE

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Hello Everyone,

Today’s profile was crazy. It exploded up over 100% on massive interest. We hope you had a chance to research it last night.

It ran all the way to 4.40 after closing yesterday just above 2 bucks. Not bad right?

We have another company on our radar for Tuesday’s session that you are going to want to pay attention to.

Pull up XXII immediately.

2nd Century Group, Inc. (Nasdaq: XXII) is the pioneering nicotine harm reduction company in the tobacco industry enabling smokers to take control of their nicotine consumption.

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They created their flagship product, the VLN® cigarette, to give traditional cigarette smokers an authentic and familiar alternative that helps them take control of their nicotine consumption. VLN® cigarettes have 95% less nicotine than the traditional cigarette and have been proven to greatly reduce nicotine consumption. Instead of offering new ways of delivering nicotine to addicted smokers, they offer smokers the option to take control of their nicotine consumption and make informed and more productive choices, including the choice to avoid addictive levels of nicotine altogether.

Their wholly owned subsidiaries include a leading cigarette manufacturer that produces all VLN® products and provides turnkey contract manufacturing for other tobacco brands both domestically and internationally. The 60,000 square foot facility in Mocksville, North Carolina has the capacity to produce more than 45 million cartons of combustible tobacco products annually with additional space for expansion.

Their proprietary reduced nicotine tobacco blends are made possible by comprehensive and patented technologies that regulate nicotine biosynthesis activities in the tobacco plant, resulting in full flavor and high yield with 95% less nicotine. Their extensive patent portfolio has been developed to ensure we have the only low nicotine combustible cigarette in the United States and critical international markets.

Currently, VLN® is available in over 5,000 stores across 26 states, but that could be just the start.

22nd Century has announced ambitious plans to extend distribution to over 270,000 retail outlets nationwide. And no stopping there. International expansion is also on its agenda, with established partnerships in markets like South Korea, that where the demand for harm-reduction products is growing. And the infrastructure for growth is in place. XXII’s supply chain includes a stockpile of low-nicotine tobacco ready to meet demand and has the additional capacity to manufacture up to 1.4 million cartons of VLN® cigarettes—enough to generate up to $85 million in revenue. In other words, XXII isn’t just poised for success; they have the infrastructure in place to meet the increasing consumer demand for their products.

On Tuesday the company announced:

22nd Century CEO & Chairman Larry Firestone Provides Corporate Update Letter to Stockholders

Corporate Update Letter Highlights Plans to Begin Profitable Growth Phase in 2025 on Expansion of Rebranded VLN® Cigarette Products

MOCKSVILLE, N.C., April 08, 2025 (GLOBE NEWSWIRE) — 22nd Century Group, Inc. (Nasdaq: XXII), a tobacco products company that is leading the fight against nicotine by offering smokers a choice about their nicotine consumption, today issued the following letter to stockholders from Larry Firestone, the Chief Executive Officer of 22nd Century Group, Inc.:

A Letter to Our Shareholders From Larry Firestone, CEO & Chairman – 22nd Century Group

It’s been 16 months since I stepped into the role of Chairman and CEO, and I’ve never been more energized by the mission we’re driving forward together.

Before diving into this update, I want to take a moment to express my genuine appreciation to every member of our team whose vital roles help 22nd Century Group change the future of nicotine consumption. Thank you!! You are the reason we’re making real progress—and the reason that we will be successful.

I’ll walk you through a few industry shifts that are working in our favor and what’s still ahead of us to achieve greatness.

Our Industry – Tobacco

Big Tobacco for decades has dominated the industry, with a market size that is over $85 billionstrong and a single mission to keep people dependent on nicotine.

At 22nd Century, we’re flipping that script. The majority of adult smokers say they want to quit, but fewer than 10% actually can. That’s where VLN® steps in. We’re not trying to reinvent the wheel—we’re redefining it. VLN® is the only FDA-authorized cigarette that puts control back in the smoker’s hands with 95% less nicotine.

There’s one big question we keep asking: What if smokers could take control of their nicotine consumption and still enjoy a cigarette?

Nicotine dependence still drives billions in healthcare costs and keeps nearly 29 million adult smokers in a cycle they want out of. Nearly half that number, 15 million try to quit every year with less than 1 in 10 succeeding.

This is why VLN® matters. We’re not asking smokers to quit—we’re giving them the option to manage their consumption without compromise. VLN® lets smokers keep the ritual, the sensation, the satisfaction—on their own terms. Real choice. Real control.

And with the FDA proposing new lower nicotine limits, VLN® already meets this standard. No scrambling needed. While others are stuck in the approval queue, we’re in the market and ready to go.

A great example of a changing landscape is the zero- and low-proof spirits trend. A few years ago, it was niche. Now, it’s a multi-billion-dollar movement. Same deal here: even if just a fraction of adult smokers switch to VLN® for whatever reason—habit, health, or just to cut back—the VLNC (Very Low Nicotine Content) category could be worth billions. And we’re the only player leading that charge.

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2024: Reset. Refocus. Relaunch

This past year was all about setting the foundation. Here’s what we have accomplished:

  • We went all-in on tobacco. Divested out of hemp, hops, or cannabis.
  • Streamlined our operations, diminished significant cash burn.
  • Slashed ~$18M in debt, strengthening our balance sheet
  • Gave VLN® a bold new look and feel with a robust go to market strategy.
  • Developed retail partnerships that’ll relaunch VLN® in thousands of stores across the U.S.

Vertical Integration, Strategic Expansion

Our core contract manufacturing (CMO) business is the backbone of our operations. It’s high-volume, low-margin—and absolutely essential to our success. We provide full turnkey services to secondary and tertiary tobacco brands providing manufacturing, compliance, and supply chain. They handle the brand. We handle everything else for them.

Here’s why CMO is a major strategic win:

  • It gives us a vertically integrated platform for our core product—we control the manufacturing, distribution, and marketing of VLN® and other proprietary products.
  • With new long-term, properly priced contracts, CMO provides revenue that addresses all of our overhead and provides stability to our operations.
  • It opens doors. We’re leveraging customer partnerships and brand equity to launch VLN® and new partner brands—growing into new channels and stores.

Starting Q2 2025, we’re hitting the market with our bold new branding, featuring:

  • VLN® Gold
  • VLN® Red
  • VLN® Green (Menthol)

Already in 5,000+ stores—and aiming for a growing slice of the 272,000-stores nationwide.

We’re also launching partner-branded VLN® products—a win-win. Our CMO customers get a premium, high-margin SKU and we get a fast track into new stores, new audiences, and greater awareness. Think of it like your favorite beverage offering a low-proof version: same vibe, less buzz, new category.

And that’s exactly where we’re headed: building the Very Low Nicotine Content (VLNC) category. Just like low-proof spirits carved out their space, VLN® will stand on its own shelf—with its own story.

2025 and Beyond: Time to Grow

We’ve stabilized. We’ve streamlined. And we’ve struck the match and created the spark.

This year is about scale—and profit. VLN® is our statement. Our CMO business is funding our freedom. We’ve got the strategy, team, and partnerships to finally take 22nd Century into self-sustaining territory.

We’re not just building a brand. We’re creating a whole new lane in the $85 Billion Dollar industry—and bringing smokers options with VLN®.

Thanks for being part of the journey.

Larry FirestoneChief Executive Officer

Products:

Reduced Nicotine Content (RNC) Tobacco Plants:

Very Low Nicotine (VLN) Cigarettes:

They offer cigarettes containing 95% less nicotine than conventional cigarettes, with the sole function of making it easier to reduce the number of cigarettes smoked.

FDA Authorization:

They received the first and only FDA MRTP authorization for a combustible cigarette in December 2021

    22nd Century Group Reports Fourth Quarter and Full Year 2024 Financial Results

    Launches 2025 Growth Strategy Leveraging Both Internal and External Brand Assets Across Multiple Categories

    Announces First VLN® Partner Brands with Smoker Friendly Ready for Shipment in Q2 2025, Additional Partner VLN® Brands in Discussion

    MOCKSVILLE, N.C., March 20, 2025 (GLOBE NEWSWIRE) — 22nd Century Group, Inc.(Nasdaq: XXII), a tobacco products company that is leading the fight against nicotine dependence and believes smokers should have a choice about their nicotine consumption, today announced results for the fourth quarter and year-ended December 31, 2024, and provided an update on recent business highlights.

    Fourth Quarter and Full Year 2024 Financial Results (compared to Third Quarter 2024, except as noted)

    All figures reported below reflect continuing operations, excluding discontinued operations related to the sale and exit of the Company’s hemp/cannabis business in late 2023.

    • Net revenues decreased sequentially to $4.0 million, compared to $5.9 million.
    • Gross profit (loss) was $(1.3) million, compared to $(0.6) million.
    • Operating loss increased to $4.1 million, compared to $3.4 million.
    • Net loss increased to $4.2 million, compared to $3.6 million.
    • Adjusted EBITDA loss was $3.9 million, from a loss of $3.2 million.
    • Ended fiscal 2024 with net debt of $3.3 million.

    Recent Business Highlights

    • Launched new VLN® branding, ready for shipment in the second quarter 2025, including a new logo, packaging and marketing plan.
    • Announced first VLN® partner brand with Smoker Friendly, ready for shipment in the second quarter of 2025.
    • Progressed in securing additional VLN® partner brands, working toward a new reduced nicotine content product category.
    • Signed a new five-year expanded license and manufacturing agreement with Smoker Friendly, covering 11 existing products and eight new premium products to be launched.
    • Announced compliance with the FDA’s proposed new tobacco product standard for nicotine yield, which cites VLN® from 22nd Century as the only combustible cigarette on the market that currently meets the new standard of a maximum nicotine level of 0.7 mg/g in cigarettes.

    “Our 2024 results demonstrate a challenging but transformative year as we worked our turnaround plan and reset almost all aspects of our business. We are starting 2025 with a new base focused on growth across all of our revenue lines. Our contract manufacturing business begins the year with profitable contracts, and we have begun the relaunch of our reduced nicotine VLN® cigarette business that will encompass both our branded VLN® products as well as private label partner VLN® products,” said Larry Firestone, Chairman and CEO. “We are excited for 2025 as this is really a new start of 22nd Century Group, Inc., and are looking forward to shaping our future around our current strategy.”

    Fourth Quarter 2024 – Discussion of Product Line Net Revenues

    • Cigarette net revenues were $3.3 million, decreased from $4.1 million in the third quarter of 2024 reflecting a shift in overall product mix and pricing between domestic and export sales. Q4 2024 cigarette carton volumes increased to 228 thousand compared to 156 thousand in the third quarter of 2024.
    • Filtered cigars net revenues decreased to $0.8 million, compared to $1.7 million in the immediately preceding quarter, reflecting lower volumes as the Company completed last time buy orders under terminated contract manufacturing agreements.
    • Cigarillo distribution net revenues were negligible in the fourth quarter compared to $0.2 million in the preceding quarter.
    • VLN® cigarette net revenues were $(0.1) million in the fourth quarter, reflective of rebate and marketing incentives for product already in distribution. The Company has announced new branding for its VLN® products, which will be ready for shipment in the second quarter 2025, as well as its first partner brand VLN® products with its existing customer Smoker Friendly. Additional partner brand agreements are in progress as part of a relaunch of its VLN® reduced nicotine content products.

    22nd Century Announces First Partner VLN Agreement, New VLN Availability with Smoker Friendly

    Smoker Friendly Adds Both VLN and Smoker Friendly Branded VLN Reduced Nicotine Content Products to its Store Lineup

    MOCKSVILLE, N.C., March 10, 2025 (GLOBE NEWSWIRE) — 22nd Century Group, Inc.(Nasdaq: XXII), a tobacco products company that is leading the fight against nicotine by offering smokers a choice about their nicotine consumption, today announced that it has signed an agreement with Smoker Friendly, one of its largest customers, to launch Smoker Friendly VLN branded reduced nicotine content cigarette products that will become the first VLN partner brand.

    The introduction of Smoker Friendly VLN and 22nd Century VLN in Smoker Friendly outlets will be one of the first presentations of gold and menthol SKU’s that introduce the new VLN branding.

    The addition of Smoker Friendly branded VLN and 22nd Century Group’s VLN products builds on a customer relationship of over 10 years, as does the recent addition of the Smoker Friendly Black Label style cigarette. The Companies are currently obtaining state approvals for these products and expect to begin shipping in the second quarter of 2025.

    Larry Firestone, Chief Executive Officer of 22nd Century, said, “We are very excited to have Smoker Friendly adopt our first VLN partner brand and also add our newly rebranded VLN products to the Smoker Friendly product offerings in their stores. This is a foundational building block to advancing VLN in the market, and will be a staged rollout as we garner state approvals. Equally important to expanding distribution will be measuring rate of sale once VLN is on the shelf.”

    Terry Gallagher, President and Chief Executive, Smoker Friendly said, “We are excited to expand our relationship and product portfolio to include the VLN lineup under our brand as well as the updated 22nd Century VLN brand products. This is an important step for the future of our partnership.”

    About The Cigarette Store LLC dba Smoker Friendly

    Boulder, Colorado based Smoker Friendly operates 344 stores in 13 states. The stores are a mix of tobacco stores, cigar lounges, liquor stores, and fueling locations under the names Smoker Friendly, Tobacco Depot, Smoke ‘N Go, Havana Manor, and Gasamat.

    The Smoker Friendly team also manages the Smoker Friendly Authorized Dealer program. This program provides a total tobacco private label portfolio, industry expertise, a well-known name, and geographic exclusivity to tobacco retailers desiring an alternative to the contracts offered by big tobacco.

    NEWS


    22nd Century CEO & Chairman Larry Firestone Provides Corporate Update Letter to Stockholders

    5 hours ago

    22nd Century Group Reports Fourth Quarter and Full Year 2024 Financial Results

    Mar 20, 2025

    22nd Century Group to Announce Fourth Quarter and Full Year 2024 Results on March 20, 2025

    Mar 14, 2025

    22nd Century Announces First Partner VLN Agreement, New VLN Availability with Smoker Friendly

    Mar 10, 2025

    Emerging Growth Research Releases New Initiation Report on the 22nd Century Group (XXII)

    Feb 19, 2025

    22nd Century to Present at the Emerging Growth Conference on February 19, 2025

    Feb 6, 2025

    22nd Century Regains Full Compliance with Nasdaq Continued Listing Standards

    Jan 27, 2025

    FDA Publishes Proposed New Tobacco Product Standard for Nicotine Yield, Citing VLN from 22nd Century as the Only Combustible Cigarette That Complies with the New Standard

    Jan 15, 2025

    Washington Post Story Featuring 22nd Century VLN Products Highlights Proposed FDA Reduced Nicotine Content Policy Could Initially Benefit An Estimated 13 Million Smokers

    Jan 14, 2025

    22nd Century Stands Ready to Support the Adoption of FDA Proposed Tobacco Product Standard to Mandate Reduced Nicotine Content in Cigarettes with its VLN Cigarettes

    Jan 13, 2025

    22nd Century Group Signs New, Expanded License and Manufacturing Agreement with Smoker Friendly

    Jan 7, 2025

    22nd Century Announces 1-for-135 Reverse Stock Split

    Dec 13, 2024

    22nd Century Applauds FDA Proposal to Mandate Reduced Nicotine Content in Cigarettes

    Dec 12, 2024

    22nd Century Group Reports Third Quarter 2024 Financial Results

    Nov 12, 2024

    22nd Century Group (XXII) to Announce Third Quarter 2024 Results on November 12, 2024

    Nov 7, 2024

    22nd Century Group to Present at the LD Micro Main Event XVII on October 30 in Los Angeles

    Oct 21, 2024

    22nd Century Regains Compliance with Nasdaq Stockholders’ Equity Requirement

    Oct 8, 2024

    22nd Century Continues CMO Business Expansion with Additional Filtered Cigar Volume

    Sep 25, 2024

    22nd Century Announces New Branded Products Order with Customer for Southeast Asia

    Sep 23, 2024

    22nd Century Updates Strategic Growth Initiatives for VLN

    Sep 11, 2024

    MANAGEMENT TEAM

    Larry Firestone

    Chief Executive Officer

    Mr. Firestone brings over 40 years of enterprise, operations, and financial management experience in both public and private companies, including tenures as CEO, CFO and COO across multiple industry sectors. Mr. Firestone most recently served as Chief Financial Officer of Oakland Manager, a privately-held purveyor of cannabis with both retail and wholesale market penetration, and as Chairman of FirePower Technology, a privately held manufacturer of ATX power supplies for the IT and instrumentation markets. In the public company sector, Mr. Firestone has served as Chief Executive Officer of Eastside Distilling, Inc. (NASDAQ: EAST), Chief Executive Officer of Qualstar Corporation (NASDAQ: QBAK), Chief Financial Officer of Advanced Energy Industries (NASDAQ: AEIS), and Chief Financial Officer of Applied Films Corporation (NASDAQ: AFCO). He has served on numerous boards, including those of Eastside Distilling, Qualstar, CVD Equipment Corporation (NASDAQ: CVD), Amtech Systems, Inc. (NASDAQ: ASYS) and HyperSpace Communications, Inc. (NYSE: HYPR). Mr. Firestone received his Bachelor of Science in Business Administration with a concentration in Accounting from Slippery Rock University of Pennsylvania.

    Anthony Johnson

    Director

    Anthony Johnson was appointed as a member of our Board of Directors in August 2021, serving on our Scientific Advisory and Compensation Committees. Anthony is co-founder, President, and CEO of Kodikaz Therapeutic Solutions, a next-generation non-viral gene therapy company. He is also a founding partner of Buffalo Biosciences, a life science strategic business management firm that supports the evaluation and commercialization of bioscience technologies from concept to market. Previously he was president and CEO of Empire Genomics, where he transformed a concept formed at a university lab into a preeminent oncology molecular diagnostic testing enterprise. He also served as the business leader of the stem cell and regenerative medicine franchise for Thermo Fisher (Invitrogen Corporation). Anthony has leveraged his business experience and numerous board positions to mentor technology startups and entrepreneurs, spur state and local job creation, and introduce STEM curriculum into early childhood education. He is an Aspen Institute Health Innovation Fellow and member of the Aspen Global Leadership Network, and he currently serves on the board of the WNED/PBS broadcasting service of Western New York. Johnson is a founding board member of the Communities of Giving Legacy Initiative, which works to create positive change in the lives of low-income youth of color. Additionally, he serves as Michigan Street African-American Heritage Corridor Commissioner and was an Opportunities Council member for University of Buffalo. He holds an MBA from Manchester Business School, Manchester, UK, with an emphasis in international strategy, and a BA in biology from Fisk University, Nashville, TN.

    Lucille S. Salhany

    Director

    Lucille S. Salhany was appointed as a member of our Board of Directors in September 2021, serving on the Corporate Governance and Nominating and Finance committees. Lucille is currently President and CEO of her own consulting company, JHMedia. She was also one of the founding partners of Echo Bridge Entertainment and CEO & President of LifeFX Networks, Inc. Prior to this, she served as Chairperson of the Twentieth Television division of Fox, and was appointed the first woman in history to head a major television network when she accepted the Chairmanship of Fox Broadcasting. After chairing Fox, Salhany accepted the post of Chief Executive Officer and President of United Paramount Network (UPN), launching and growing UPN to become the fifth major broadcast network. She also served on the Board of Directors for Echo Bridge Entertainment, Compaq / Hewlett-Packard, Fox, Inc., Avid Technologies, and American Media, Inc. Lucille was also a trustee of Emerson College and Lasell College, where she received Honorary Doctorates.

    Andy Arno

    Director

    Mr. Arno previously served, until February 2023, as Vice Chairman of The Special Equities Group, a division of Dawson James Securities, Inc., plus other senior roles at investment banking firms. Prior, Mr. Arno served as Vice Chairman and Chief Marketing Officer of Unterberg Capital, LLC, an investment advisory firm that he co-founded, and as Vice Chairman and Head of Equity Capital Markets of Merriman Capital LLC, where he also served on the board of the parent company, Merriman Holdings, Inc. Mr. Arno was responsible for Capital Markets for C.E. Unterberg, Towbin, a Vice President at Lehman Brothers and in the Individual Investors Services Division of L.F. Rothschild Unterberg, Towbin in portfolio management for high-net-worth individuals. Mr. Arno is currently the Chairman of the Board of Oncocyte Corporation and also serves on the boards of directors of Smith Micro Software, Inc., Independa Inc., and Comhear Inc. Mr. Arno previously served as a director of Asterias Biotherapeutics, Inc. from August 2014 until it was acquired by Lineage Cell Therapeutics, Inc. in March 2019. Mr. Arno received a BS degree from George Washington University.

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